If you answered ‘yes’ to these questions you may be eligible to participate as a volunteer in the CryoStim^TM clinical trial which will test the effects (good and bad) of an experimental  cancer vaccine combining the study drug  called AlloStim™ with a procedure to kill a sample of your tumor by freezing it in place with extreme cold.

The tumor freezing procedure is a minimally invasive and relatively painless procedure that uses a FDA approved medical device. The procedure is called percutaneous cryoablation and is performed by inserting a probe through your skin into a selected tumor lesion under the guidance of a CT scan image.  Argon gas is released into the tumor through the probe which creates a controlled ice ball sculptured to the shape of your tumor resulting in tumor death.  The AlloStim™ experimental drug is then injected into the dead tumor lesion.

The combination of the antigens released from the dead tumor tissue and AlloStim™ as an immune system adjuvant creates an experimental cancer vaccine designed to educate your immune system to identify the tumor as a danger to the body and stimulate an immune response against tumors that reside in untreated parts of the body.  AlloStim™ contains bio-engineered immune cells associated with monoclonal antibody coated microbeads.

This approach was developed by researchers at Hadassah-Hebrew University Medical Center in Jerusalem and has demonstrated promise in animal testing of a variety of cancers and is now being tested in patients in the United States after having obtained FDA clearance of an Investigational New Drug (IND) application.

To learn more about the clinical trial and to determine if you might qualify click on the subjects on the main menu to the left or register on the site to begin the screening process